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TribioScience | SKU: TBI1039-5MG

MK-571, Leukotriene Cys LT1 antagonist (TBI1039)

Name: MK-571, Leukotriene Cys LT1 antagonist (TBI1039)
Brand: TribioScience
SKU: TBI1039-5MG
Price: 108.0 USD
Availability: InStock

$108.00

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TribioScience

MK-571, Leukotriene Cys LT1 antagonist (TBI1039)

From $108.00

Description

Product Details

Formal Name: 5-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, sodium salt

Alternate Names: L-660711

Molecular Formula: C₂₆H₂₆ClN₂O₃S₂ · Na

Formula Weight: 537.10

CAS Number: 115104-28-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 50 mg/ml).

Storage: RT

Stability: ≥ 1 year.

Applications

Leukotriene Cys LT1 antagonist

Functions

Potent (EC50 = 1.3nM) and selective Leukotriene D4 antagonist(LTD4) displaying inverse agonist activity, Blocks binding of LTD4 to human (Ki = 0.22 nM) and guinea pig (Ki = 2.1 nM) lung membranes. Selective for the CysLT1 receptor. Multidrug resistance protein 1 (MRP1) inhibitor.