MHY-1485, mTOR activator (TBI1604)

Description

Product Details

Formal Name: 4,6-Di-4-morpholinyl-N-(4-nitrophenyl)-1,3,5-triazin-2-amine

Molecular Formula: C₁₇H₂₁N₇O₄

Formula Weight: 387.39

CAS Number: 326914-06-1

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 20 mg/ml) or in DMF (up to 10 mg/ml)

Storage: RT

Stability: ≥ 1 year.

Applications

mTOR activator

Functions

mTOR activator. Suppresses autophagy by inhibiting the fusion of autophagosomes with lysosomes leading to the accumulation of enlarged autophagosomes. Increases ovarian follicle development. Displays cellular protective effects from cytotoxic doses of dexamethasone or UV radiation. A useful tool for probing the cellular role of mTOR. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 20 mg/ml) or in DMF (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.