LY-171883, Leukotriene Cys LT1 antagonist (TBI1052)

Description

Product Details

Formal Name: 1-[2-Hydroxy-3-propyl-4-[4-1H-tetrazol-5-yl)butoxy]phenyl]ethanone

Molecular Formula: C₁₆H₂₂N₄O₃

Formula Weight: 318.37

CAS Number: 88107-10-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

Leukotriene Cys LT1 antagonist

Functions

LY-171883 is a selective and orally active leukotriene D4 (LTD4) antagonist (Ki = 0.63 µM). It is also an activator of peroxisome proliferator-activated receptors (PPAR’s).

Application Procedures

First dissolved in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.