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TribioScience | SKU: TBI4670-5MG

Liproxstatin-1, Ferroptosis inhibitor (TBI4670)

Name: Liproxstatin-1, Ferroptosis inhibitor (TBI4670)
Brand: TribioScience
SKU: TBI4670-5MG
Price: 117.0 USD
Availability: InStock

$117.00

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TribioScience

Liproxstatin-1, Ferroptosis inhibitor (TBI4670)

From $117.00

Description

Product Details

Formal Name: N-[(3-Chlorophenyl)methyl]spiro[1,4-dihydroquinoxaline-3,4’-piperidine]-2-amine

Molecular Formula: C₁₉H₂₁ClN₄

Formula Weight: 340.85

CAS Number: 950455-15-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 15 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

Ferroptosis inhibitor

Functions

Ferroptosis inhibitor (IC50 = 22 nM) that mitigates tissue injury in a mouse model of hepatic ischemia/reperfusion injury. It protected mouse myocardium against ischemia/reperfusion injury via a decrease in VDAC1 and restoration of GPX4 levels. Liproxstatin-1’s mechanism of activity has been attributed to its activity as a radical-trapping antioxidant.