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TribioScience  |  SKU: TBI2084-200UG

Leptomycin B, Nuclear export inhibitor (TBI2084)

$108.00
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TribioScience

Leptomycin B, Nuclear export inhibitor (TBI2084)

From $108.00

Description

Product Details

Molecular Formula: C33H48O6

Formula Weight: 540.75

CAS Number: 87081-35-4

Purity: >98%

Formulation: Soln in ethanol

Solubility: Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO.

Storage: -20°C

Stability: ≥ 1 year.

Applications

Nuclear export inhibitor

Functions

Inhibitor of nuclear export of proteins. Acts via covalent binding to and inhibiting CRM1/exportin-11. Inhibits the nuclear export of the HIV regulatory protein Rev2. Stabilizes p53 by blocking its nuclear export3.

Application Procedures

Solutions in DMSO are unstable and must be used within one working day. Do not store DMSO solutions.

Option

  • 200 µg
  • 1 MG
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