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TribioScience | SKU: TBI3193-10MG

Leonurine, Neuroinflammation inhibitor (TBI3193)

Name: Leonurine, Neuroinflammation inhibitor (TBI3193)
Brand: TribioScience
SKU: TBI3193-10MG
Price: 86.0 USD
Availability: InStock

$86.00

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Product Description

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TribioScience

Leonurine, Neuroinflammation inhibitor (TBI3193)

From $86.00

Description

Product Details

Formal Name: 4-guanidinobutyl 4-hydroxy-3,5-dimethoxybenzoate

Alternate Names: SCM-198

Molecular Formula: C₁₄H₂₁N₃O₅

Formula Weight: 311.33

CAS Number: 24697-74-3

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

Neuroinflammation inhibitor

Functions

Inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-κB pathways. Inhibits the formation of advanced glycation end products. Ameliorates cognitive dysfunction by antagonizing exocytotoxic glutamate insults and inhibiting autophagy. Attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4. Attenuates early atherosclerotic lesions in hypercholest-erolemic rabbits via modulation of the inflammatory and oxidative stress pathways.