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TribioScience  |  SKU: TBI2884-10MG

L-NMMA, pan-specific NOS inhibitor (TBI2884)

$63.00
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TribioScience

L-NMMA, pan-specific NOS inhibitor (TBI2884)

From $63.00

Description

Product Details

Alternate Names: NG-monomethyl-l-arginine

Molecular Formula: C7H16N4O3 • CH2COOH

Formula Weight: 248.30

CAS Number: 53308-83-1

Purity: >98%

Formulation: powder

Solubility: Soluble in Water (up to 10 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

pan-specific NOS inhibitor

Functions

Inhibitor of neuronal, endothelial cell and macrophase nitric oxide synthases (nNOS, eNOS and iNOS, respectively). L-NMMA acted as a mechanism-based irreversible inhibitor exhibiting time- and concentration-dependent inactivation of iNOS with a Ki-2.6 µM. When assayed without a preincubation period it acted as a typical reversible inhibitor of iNOS, Ki=3.9 µM. It also reversibly inhibited nNOS and eNOS with Kis =0.65 and 0.7 µM respectively.

Application Procedures

First dissolved in Water (up to 10 mg/ml), then diluted to aqueous buffer.

Option

  • 10 MG
  • 50 MG
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