Welcome to Astor Scientific

New collections added! Learn more

TribioScience  |  SKU: TBI5393-5MG

Isohelenin, NFkB inhibitor (TBI5393)

$90.00
Shipping calculated at checkout.


Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Payment & Security

Payment methods

  • American Express
  • Apple Pay
  • Diners Club
  • Discover
  • Google Pay
  • Mastercard
  • PayPal
  • Shop Pay
  • Venmo
  • Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.


Product Description


Product Reviews

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)
TribioScience

Isohelenin, NFkB inhibitor (TBI5393)

From $90.00

Description

Product Details

Formal Name: (3aR,8aR,9aR)-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one

Alternate Names: Isoalantolactone

Molecular Formula: C15H20O2

Formula Weight: 232.30

CAS Number: 470-17-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (50 mg/ml); or Ethanol (30 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

NFkB inhibitor

Functions

A sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFkB (complete inhibition at 5 µM) acting via inhibition of IKKß6. Isohelenin-mediated NFkB inhibition suppresses IL-8 expression, iNOS expression and RANTES biosynthesis. Displays protective effects in endotoxic shock in rodent models. Induces apoptosis in glioma cells.

Application Procedures

First dissolved in DMSO (50 mg/ml); or Ethanol (30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Option

  • 5 MG
  • 25 MG
View product
close
close
I have a question
sparkles
close
product
Hello! I am very interested in this product.
gift
Special Deal!
sparkles