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TribioScience | SKU: TBI1513-5MG

IQ-1S, JNK3 inhibitor (TBI1513)

Name: IQ-1S, JNK3 inhibitor (TBI1513)
Brand: TribioScience
SKU: TBI1513-5MG
Price: 90.0 USD
Availability: InStock

$90.00

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TribioScience

IQ-1S, JNK3 inhibitor (TBI1513)

From $90.00

Description

Product Details

Formal Name: 11H-Indeno[1,2-b]quinoxaline-11-one oxime, sodium salt

Molecular Formula: C₁₅H₈N₃O ∙ Na

Formula Weight: 269.23

CAS Number: 23146-22-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 15 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

JNK3 inhibitor

Functions

JNK3 inhibitor (Kd = 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively). Displays anti-inflammatory and immunosuppresive activity. Inhibits LPS-induced proinflammatory cytokine and nitric oxide release in vitro. Attenuates collagen-induced arthritis severity and inhibits murine delayed-type hypersensitivity in vivo.