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TribioScience  |  SKU: TBI1426-5MG

IOX 1, JMJD demethylase inhibitor (TBI1426)

$129.60
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TribioScience

IOX 1, JMJD demethylase inhibitor (TBI1426)

From $129.60

Description

Product Details

Formal Name: 8-Hydroxy-5-quinolinecarboxylic acid

Alternate Names: 5-Carboxy-8HQ

Molecular Formula: C10H7NO3

Formula Weight: 189.17

CAS Number: 5852-78-8

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 20 mg/ml).

Storage: RT

Stability: ≥ 1 year.

Applications

JMJD demethylase inhibitor

Functions

Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling. Cell permeable

Application Procedures

First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.

Option

  • 5 MG
  • 25 MG
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