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TribioScience | SKU: TBI3881-5MG

iGP-1, Mitochondrial glyceraldehyde-3-phosphate dehydrogenase inhibitor (TBI3881)

Name: iGP-1, Mitochondrial glyceraldehyde-3-phosphate dehydrogenase inhibitor (TBI3881)
Brand: TribioScience
SKU: TBI3881-5MG
Price: 90.0 USD
Availability: InStock

$90.00

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TribioScience

iGP-1, Mitochondrial glyceraldehyde-3-phosphate dehydrogenase inhibitor (TBI3881)

From $90.00

Description

Product Details

Formal Name: N-[4-(1H-Benzoimidazol-2-yl)-phenyl]-succinamic acid

Molecular Formula: C₁₇H₁₅N₃O₃

Formula Weight: 309.30

CAS Number: 27031-00-1

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO up to 50 mg/ml

Storage: -20°C

Stability: ≥ 1 year.

Applications

Mitochondrial glyceraldehyde-3-phosphate dehydrogenase inhibitor

Functions

A potent and cell permeable inhibitor of the mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6.3 μM, which is selective over the cytosolic enzyme. It does not block pyruvate uptake into cells or mitochondria and has no direct effect on glycolysis in synaptosomes. This novel inhibitor is a unique tool which may be used to investigate the role of glycerol-3-phosphate metabolism in isolated and intact systems.