| Description |
Recombinant Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe23-Ser1122(ITGA10)acidic tail & Gln21-Asp728(ITGB1)basic tail. |
| Purity |
> 90% as determined by Tris-Bis PAGE |
| Accession |
O75578-1(ITGA10)&P05556-1(ITGB1) |
| Target Symbol |
Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer |
| Species |
Human |
| Expression System |
HEK293 |
| Tag |
C-His |
| Expression Range |
Phe23-Ser1122(ITGA10)acidic tail & Gln21-Asp728(ITGB1)basic tail |
| Mol. Weight |
The protein has a predicted MW of 125.60 kDa (ITGA10) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 140-160 kDa (ITGA10) and 100-130 kDa (ITGB1) based on Tris-Bis PAGE result. |
| Form |
Lyophilized |
| Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping |
Shipped at ambient temperature. |
| Gene Background |
Alpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. α10β1 is likely to be expressed only by a subset of fibroblasts. |