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Product Description
Description
Interleukin 12 (IL-12) is an anti-inflammatory cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit, also known as a natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF). The IL-12 and IL-23 (another heterodimeric cytokine) share the p40 subunit. IL-12 inhibits the synthesis of numbers of cytokines, including IFN-gamma, IL-2, IL-3, TNF, and GM-CSF produced by activated macrophages and by helper T-cells.
TYPICAL DATA
This standard curve(R2=1.000) is provided for demonstration only. A standard curve should be generated for each set of samples assayed.
SENSITIVITY
The minimum detectable dose (MOD) of human IL-12/IL-23 p40 is typically 5 pg/ml.
The Intra-CV is < 10%, the Inter-CV is < 12%.
SPECIFICITY
This assay recognizes natural and recombinant human IL-12/IL-23 P40.
Interleukin 12 (IL-12) is an anti-inflammatory cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit, also known as a natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF). The IL-12 and IL-23 (another heterodimeric cytokine) share the p40 subunit. IL-12 inhibits the synthesis of numbers of cytokines, including IFN-gamma, IL-2, IL-3, TNF, and GM-CSF produced by activated macrophages and by helper T-cells.
TYPICAL DATA
This standard curve(R2=1.000) is provided for demonstration only. A standard curve should be generated for each set of samples assayed.
SENSITIVITY
The minimum detectable dose (MOD) of human IL-12/IL-23 p40 is typically 5 pg/ml.
The Intra-CV is < 10%, the Inter-CV is < 12%.
SPECIFICITY
This assay recognizes natural and recombinant human IL-12/IL-23 P40.
