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TribioScience  |  SKU: TBI4678-5MG

GO289, Casein kinase 2 inhibitor (TBI4678)

$171.00
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TribioScience

GO289, Casein kinase 2 inhibitor (TBI4678)

From $171.00

Description

Product Details

Formal Name: (E)-5-Bromo-2-methoxy-4-(((3-(methylthio)-5-phenyl-4H-1,2,4-4-yl)imino)methyl)phenol

Molecular Formula: C17H15BrN4O2S

Formula Weight: 419.30

CAS Number: 694522-87-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to at least 25 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

Casein kinase 2 inhibitor

Functions

Potent inhibitor of casein kinase 2 (CK2; IC50 = 7 nM). Showed no inhibition of DYRK, HIPK, CLK, and PIM family kinases. It is a circadian clock modifier that caused strong period lengthening. Growth of MLL-AF9 leukemia cells was strongly inhibited by GO289.

Application Procedures

First dissolved in DMSO (up to at least 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Option

  • 5 MG
  • 25 MG
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