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TribioScience | SKU: TBI1328-10MG

FH-535, Wnt/β-catenin inhibitor (TBI1328)

Name: FH-535, Wnt/β-catenin inhibitor (TBI1328)
Brand: TribioScience
SKU: TBI1328-10MG
Price: 99.0 USD
Availability: InStock

$99.00

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TribioScience

FH-535, Wnt/β-catenin inhibitor (TBI1328)

From $99.00

Description

Product Details

Formal Name: 2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide

Molecular Formula: C₁₃H₁₀Cl₂N₂O₄S

Formula Weight: 361.21

CAS Number: 108409-83-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

Wnt/β-catenin inhibitor

Functions

Suppresses Wnt/β-catenin signaling. It antagonizes PPARγ and PPARδ ligand-dependent activation which is mediated by inhibition of recruitment of the coactivators β-catenin and GRIP1 but not the corepressors NCoR and SMRT1. Inhibits the migration and growth of breast cancer cell lines as well as colon, lung and liver cell lines. Useful tool for probing the involvement of Wnt signaling pathway.