Felodipine, L-type Ca2+ channel blocker (TBI2020)

Description

Product Details

Formal Name: 3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Molecular Formula: C₁₈H₁₉C_l2NO₄

Formula Weight: 384.25

CAS Number: 72509-76-3

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 35 mg/ml).

Storage: RT

Stability: ≥ 1 year.

Applications

L-type Ca2+ channel blocker

Functions

Felodipine is a potent L-type Ca2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels. It displays high vascular selectivity over cardiac muscle, thus lowering arterial blood pressure without altering cardiac contractility. Felodipine is used in the clinic as an antihypertensive agent.

Application Procedures

First dissolved in DMSO (up to 35 mg/ml) or in Ethanol (up to 35 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.