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TribioScience | SKU: TBI4731-5MG

Etomoxir (+) Na, Carnitine palmitoyltransferase Inhibitor (TBI4731)

Name: Etomoxir (+) Na, Carnitine palmitoyltransferase Inhibitor (TBI4731)
Brand: TribioScience
SKU: TBI4731-5MG
Price: 126.0 USD
Availability: InStock

$126.00

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TribioScience

Etomoxir (+) Na, Carnitine palmitoyltransferase Inhibitor (TBI4731)

From $126.00

Description

Product Details

Formal Name: (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt

Molecular Formula: C₁₅H₁₈ClO₄·Na

Formula Weight: 320.74

CAS Number: 828934-41-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 5 mg/ml with warming)

Storage: -20°C

Stability: ≥ 1 year.

Applications

Carnitine palmitoyltransferase Inhibitor

Functions

Etomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1). It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease, diabetes, and cancer. Use of etomoxir in concentrations greater than 5 µM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations. 200 µM etomoxir inhibited complex I of the electron transport chain.