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TribioScience  |  SKU: TBI2668-10MG

Diphenylene iodonium chloride, Flavoprotein inhibitor (TBI2668)

$99.00
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TribioScience

Diphenylene iodonium chloride, Flavoprotein inhibitor (TBI2668)

From $99.00

Description

Product Details

Alternate Names: DPI

Molecular Formula: C12H8I ·Cl

Formula Weight: 314.55

CAS Number: 4673-26-1

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 5 mg/ml, with warming).

Storage: -20°C

Stability: ≥ 1 year.

Applications

Flavoprotein inhibitor

Functions

An irreversible inhibitor of iNOS and eNOS (IC50s=50 and 100 nM respectively. Binds to and inhibits the flavoprotein of neutrophil NADPH oxidase. Novel agonist for GPR3. Inhibits NFκB activation induced by IL-1β. Prevents early alcohol-induced liver injury in rodent models.

Application Procedures

First dissolved in DMSO (up to 5 mg/ml, with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.

Option

  • 10 MG
  • 50 MG
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