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TribioScience  |  SKU: TBI3400-10MG

Dihydroergotamine mesylate, Serotonin receptor agonist (TBI3400)

$54.00
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TribioScience

Dihydroergotamine mesylate, Serotonin receptor agonist (TBI3400)

From $54.00

Description

Product Details

Formal Name: (5’a,10a)-9,10-Dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)ergotaman-3′,6′,18-trione, mesylate

Molecular Formula: C33H37N5O5 • CH3SO3H

Formula Weight: 679.80

CAS Number: 6190-39-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (25 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

Serotonin receptor agonist

Functions

Full agonist at serotonin 5HT1B and 5HT1D receptors, IC50= 2 and 2.2 nM respectively and also at 5HT1A and 5HT1F receptors. One of the oldest agents for treatment of migraine. Also acts as a potent vasoconstrictor and alpha-adrenergic antagonist.

Application Procedures

First dissolved in DMSO (25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.

Option

  • 10 MG
  • 50 MG
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