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TribioScience | SKU: TBI3103-5MG

Deltamethrin, Calcineurin inhibitor; Displays neurotrophic activity (TBI3103)

Name: Deltamethrin, Calcineurin inhibitor; Displays neurotrophic activity (TBI3103)
Brand: TribioScience
SKU: TBI3103-5MG
Price: 90.0 USD
Availability: InStock

$90.00

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TribioScience

Deltamethrin, Calcineurin inhibitor; Displays neurotrophic activity (TBI3103)

From $90.00

Description

Product Details

Formal Name: (S)-α-Cyano-3-phenoxybenzyl (1R, 3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate

Alternate Names: Decamethrin

Molecular Formula: C₂₂H₁₉Br₂NO₃

Formula Weight: 505.20

CAS Number: 52918-63-5

Purity: >98%

Formulation: powder

Solubility: Soluble in DSMO (up to 50 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

Calcineurin inhibitor; Displays neurotrophic activity

Functions

Deltamethrin is reported to be an inhibitor of calcineurin (PP2B), IC50~100 pM but this activity has been disputed. Markedly enhances the expression of BDNF in cultured rat cortical neurons and displays neurotrophic effects. Produces antidepressant-like effects in mice. Blocks the spontaneous down-regulation of Nav1.8 sodium channels expressed in Xenopus oocytes.