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TribioScience | SKU: TBI4930-10MG

Darunavir, HIV-1 protease inhibitor (TBI4930)

Name: Darunavir, HIV-1 protease inhibitor (TBI4930)
Brand: TribioScience
SKU: TBI4930-10MG
Price: 108.0 USD
Availability: InStock

$108.00

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TribioScience

Darunavir, HIV-1 protease inhibitor (TBI4930)

From $108.00

Description

Product Details

Formal Name: [(3aS,4R,6aR)-2,3,3a,5,6a-Hexahydrofuro[2,3-b]furan-4-yl] N-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate

Alternate Names: UIC-94017; TMC114

Molecular Formula: C₂₇H₃₇N₃O₇S

Formula Weight: 657.70

CAS Number: 206361-99-1

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 25 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

HIV-1 protease inhibitor

Functions

Darunavir is a very potent (IC50 = 3 nM against lab HIV-1 strains and clinical isolates) HIV-1 protease inhibitor that is in clinical use. Also potent against multi-PI-resistant HIV-1 strains from patient samples. Darunavir has been investigated as a potential anti-SARS-CoV2 therapeutic with mixed results.