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TribioScience  |  SKU: TBI1493-5MG

CFM-4, CARP-1 mimetic (TBI1493)

$126.00
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TribioScience

CFM-4, CARP-1 mimetic (TBI1493)

From $126.00

Description

Product Details

Formal Name: 1-[(2-Chlorophenyl)methyl]-5′-phenyl-spiro[3H-indole-3,2′(3’H)-[1,3,4]thiadiazol]-2(1H)-one

Molecular Formula: C22H16ClN3OS

Formula Weight: 405.90

CAS Number: 331458-02-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (greater than 25 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

CARP-1 mimetic

Functions

CARP-1 functional mimetic. Interferes with CARP-1 binding to APC-2 (IC50=10-15 μM). Enhances CARP-1 expression and induces G2/M cell cycle arrest. Induces apoptosis and suppresses growth of medulloblastoma cells and malignant pleural mesothelioma cells.

Application Procedures

First dissolved in DMSO (greater than 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Option

  • 5 MG
  • 25 MG
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