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TribioScience  |  SKU: TBI5592-20MG

Altretamine, GPX4 inhibitor; Ferroptosis inducer (TBI5592)

$63.00
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TribioScience

Altretamine, GPX4 inhibitor; Ferroptosis inducer (TBI5592)

From $63.00

Description

Product Details

Formal Name: N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine; 2,4,6-Tris(dimethylamino)-1,3,5-triazine

Alternate Names: Hexamethylmelamine; NSC-13875

Molecular Formula: C9H18N6

Formula Weight: 210.30

CAS Number: 645-05-6

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (40 mg/ml)

Storage: RT

Stability: ≥ 1 year.

Applications

GPX4 inhibitor; Ferroptosis inducer

Functions

Induces ferroptosis by inhibiting glutathione peroxidase 4 (GPX4) which causes accumulation of lipid hydroperoxides. Ferroptosis induction may be its mechanism of action as a cancer chemotherapeutic. Clinically useful agent for ovarian cancer.

Application Procedures

First dissolved in DMSO (40 mg/ml), then diluted to aqueous buffer.

Option

  • 20 MG
  • 100 MG
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