Y-27632 2HCl, ROCK family kinase inhibitor (TBI2301)

Description

Product Details

Formal Name: (R)-(+)-trans-4-(1-Aminoethyl)-N-(-4-pyridyl)cyclohexanecarboxamide dihydrochloride

Molecular Formula: C₁₄H₂₁N₃O · 2HCl

Formula Weight: 320.26

CAS Number: 129830-38-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO up to 25 mg/ml) or in Methanol (up to 25 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

ROCK family kinase inhibitor

Functions

Specific inhibitor of ROCK family kinases. Enhances stem cell survival and proliferation in culture. Significantly improves freeze/thaw survival rate for human embryonic stem cells without influencing morphology, karyotype, cell surface markers, or differentiation potential.

Application Procedures

First dissolved in DMSO up to 25 mg/ml) or in Methanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.