| Product Name |
Recombinant Mouse Ig γ-1 Chain C Region/IGHG1Protein Protein |
| Product Overview |
This Recombinant Mouse Ig γ-1 Chain C Region/IGHG1Protein Protein with amino acids Pro99-Lys324 is expressed in Mammalian Cell. The protein is supplied lyophilized and formulated in Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose.It has a purity >95% as determined by SDS-PAGE. |
| Target Uniprot Id |
P01857 |
| Synonyms |
g gamma-1 chain C region;IGHG1 |
| Species |
Mouse |
| Predicted Molecular Mass |
41.5 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
99-324aa |
| Purity |
>95% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer, Immunology |
| Target Function |
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. |
| Subcellular Location |
Secreted. Cell membrane. |
| Associated Diseases |
Multiple myeloma (MM) |
