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TribioScience | SKU: TBI4543-5MG

ML-167, Clk4 inhibitor (TBI4543)

Name: ML-167, Clk4 inhibitor (TBI4543)
Brand: TribioScience
SKU: TBI4543-5MG
Price: 135.0 USD
Availability: InStock

$135.00

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Product Description

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TribioScience

ML-167, Clk4 inhibitor (TBI4543)

From $135.00

Description

Product Details

Formal Name: [5-[4-[(5-Methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol

Alternate Names: CID 44968231

Molecular Formula: C₁₉H₁₇N₂O₃

Formula Weight: 335.36

CAS Number: 1285702-20-6

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (greater than 25 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

Clk4 inhibitor

Functions

ML167 is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) – IC50 = 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 µM), Clk2(1.65µM), Clk3(>10µM), Dyrk1A(>10µM), and Dyrk1B(4.4 µM).