Leupeptin hemisulfate, Trypsin-like and cysteine protease inhibitor

Description

Product Details

Formal Name: N-acetyl-L-leucyl-L-leucyl-L-argininal, hemisulfate

Alternate Names: Ac-Leu-Leu-Arg-CHO

Molecular Formula: C₂₀H₃₈N₆O₄ • 1/2H₂SO₄

Formula Weight: 475.60

CAS Number: 103476-89-7

Purity: >95%; peptide content >85%

Formulation: powder

Solubility: Soluble in Water (up to 50 mg/ml). Also soluble in ethanol and methanol

Storage: -20°C

Stability: ≥ 2 years.

Applications

Trypsin-like and cysteine protease inhibitor

Functions

A reversible inhibitor of trypsin-like proteases and cysteine proteases. Inhibits trypsin, plasmin, papain and cathepsin B, H and L. Blocks various apoptotic pathways in T cells. Commonly used in cell lysis buffers to protect proteins from degradation. Typical working concentration is 1µM (0.5 µg/ml). Origin: synthetic

Application Procedures

First dissolved in Water (up to 50 mg/ml), in ethanol or in methanol, then diluted to aqueous buffer. Solutions in distilled water, ethanol or methanol may be stored at -20°C for up to 3 months.