| Product Name |
Recombinant Human TXNRD1 (TXNRD2) Protein |
| Product Overview |
This recombinant human TXNRD1 (TXNRD2) protein includes amino acids 161-649aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q9NNW7 |
| Recommended Name |
Thioredoxin reductase 2, mitochondrial |
| Gene Name |
TXNRD2 |
| Synonyms |
Thioredoxin reductase 1, GRIM-12, TR, TR1, TRXR1, TXNR |
| Species |
Human |
| Predicted Molecular Mass |
55.9 kDa |
| Expression System |
E.coli |
| Expression Range |
161-649aa |
| Tag |
N-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Others |
| Target Function |
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. |
| Subcellular Location |
Mitochondrion. |
| Protein Family |
Class-I pyridine nucleotide-disulfide oxidoreductase family |
| Tissue Specificity |
Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608 |
