| Product Name |
Recombinant Human 4-1BB/TNFRSF9/CD137 (TNFSF9) Protein |
| Product Overview |
This recombinant human 4-1BB/TNFRSF9/CD137 (TNFSF9) protein includes amino acids 24-186aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P41273 |
| Recommended Name |
Tumor necrosis factor ligand superfamily member 9 |
| Gene Name |
TNFSF9 |
| Synonyms |
CD137;ILA;TNFRSF9;4-1BB ligand receptor;CDw137;T-cell antigen 4-1BB homolog;T-cell antigen ILA |
| Species |
Human |
| Predicted Molecular Mass |
44.0 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
24-186aa |
| Tag |
C-Fc-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer, Immunology |
| Target Function |
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. |
| Subcellular Location |
Membrane; Single-pass type II membrane protein. |
| Protein Family |
Tumor necrosis factor family |
| Tissue Specificity |
Expressed in brain, placenta, lung, skeletal muscle and kidney. |
