| Product Name |
Recombinant Human TIMP4 Protein |
| Product Overview |
This recombinant human TIMP4 protein includes amino acids 30-224aa of the target gene is expressed in Baculovirus-Insect Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q99727 |
| Recommended Name |
Metalloproteinase inhibitor 4 |
| Gene Name |
TIMP4 |
| Synonyms |
Metalloproteinase inhibitor 4 , TIMP4, TIMP-4, Metalloproteinase inhibitor 4TIMP 4, TIMP metallopept |
| Species |
Human |
| Predicted Molecular Mass |
23.5 kDa |
| Expression System |
Insect Cell |
| Expression Range |
30-224aa |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cardiovascular, Cancer |
| Target Function |
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9. |
| Subcellular Location |
Secreted. |
| Protein Family |
Protease inhibitor I35 (TIMP) family |
| Tissue Specificity |
Abundant in heart and present at low levels in many other tissues. |
