| Product Name |
Recombinant Human Thyroid Hormone Responsive (THRSP) Protein |
| Product Overview |
This recombinant human Thyroid Hormone Responsive (THRSP) protein includes amino acids 1-146aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q92748 |
| Recommended Name |
Thyroid hormone-inducible hepatic protein |
| Gene Name |
THRSP |
| Synonyms |
Thyroid hormone-inducible hepatic protein, Lpgp, LPGP1, S14, SPOT14, THRP |
| Species |
Human |
| Predicted Molecular Mass |
21 kDa |
| Expression System |
E.coli |
| Expression Range |
1-146aa |
| Tag |
N-6His |
| Purity |
>95% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. |
| Subcellular Location |
Nucleus. Cytoplasm. |
| Protein Family |
SPOT14 family |
| Tissue Specificity |
Mainly expressed in tissues that synthesize triglycerides. |
