| Product Name |
Recombinant Human Sulfotransferase 2B1 (SULT2B1) Protein |
| Product Overview |
This recombinant human Sulfotransferase 2B1 (SULT2B1) protein includes amino acids 1-365aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
O00204 |
| Recommended Name |
Sulfotransferase 2B1 |
| Gene Name |
SULT2B1 |
| Synonyms |
HSST2, ST2B1, Sulfotransferase family cytosolic 2B member 1 isoform b Alcohol sulfotransferase, EC 2 |
| Species |
Human |
| Predicted Molecular Mass |
41.3 kDa |
| Expression System |
E.coli |
| Expression Range |
1-365aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cardiovascular |
| Target Function |
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it has also significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation.; Sulfonates pregnenolone but not cholesterol. |
| Subcellular Location |
Cytoplasm, cytosol. Microsome. Nucleus. |
| Protein Family |
Sulfotransferase 1 family |
| Associated Diseases |
Ichthyosis, congenital, autosomal recessive 14 (ARCI14) |
| Tissue Specificity |
Expressed in the stratum granulosum-stratum corneum junction in the skin (at protein level). Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung. |
