| Product Name |
Recombinant Human Surfactant Associated D (SPD/SFTPD) Protein |
| Product Overview |
This recombinant human Surfactant Associated D (SPD/SFTPD) protein includes amino acids 21-375aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P35247 |
| Recommended Name |
Pulmonary surfactant-associated protein D |
| Gene Name |
SFTPD |
| Synonyms |
Pulmonary surfactant-associated protein D precursor, COLEC7, PSP-D, SFTP4, SP-D |
| Species |
Human |
| Predicted Molecular Mass |
43 kDa |
| Expression System |
E.coli |
| Expression Range |
21-375aa |
| Tag |
N-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer |
| Target Function |
Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. |
| Subcellular Location |
Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film. |
| Protein Family |
SFTPD family |
| Tissue Specificity |
Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes). |
