| Product Name |
Recombinant Human MYC Associated Factor X (MAX) Protein |
| Product Overview |
This recombinant human MYC Associated Factor X (MAX) protein includes amino acids 2-160aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P61244 |
| Recommended Name |
Protein max |
| Gene Name |
MAX |
| Synonyms |
MYC associated factor X, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8 |
| Species |
Human |
| Predicted Molecular Mass |
48 kDa |
| Expression System |
E.coli |
| Expression Range |
2-160aa |
| Tag |
N-His-GST |
| Purity |
>95% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Epigenetics And Nuclear Signaling |
| Target Function |
Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements. |
| Subcellular Location |
Nucleus. Cell projection, dendrite. |
| Protein Family |
MAX family |
| Associated Diseases |
Pheochromocytoma (PCC) |
| Tissue Specificity |
High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. |
