| Product Name |
Recombinant Human Lipopolysaccharide-Binding (LBP) Protein |
| Product Overview |
This recombinant human Lipopolysaccharide-Binding (LBP) protein includes amino acids 26-481aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P18428 |
| Recommended Name |
Lipopolysaccharide-binding protein |
| Gene Name |
LBP |
| Synonyms |
Lipopolysaccharide-Binding Protein; LBP |
| Species |
Human |
| Predicted Molecular Mass |
52.0 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
26-481aa |
| Tag |
C-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide. |
| Subcellular Location |
Secreted. Cytoplasmic granule membrane. |
| Protein Family |
BPI/LBP/Plunc superfamily, BPI/LBP family |
| Tissue Specificity |
Detected in blood serum (at protein level). |
