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Astor Scientific  |  SKU: ASTP7608

Human HBEGF (Proheparin-Binding Egf-Like Growth Factor) - Recombinant Protein

Molecule: HBEGF
Species: Human
Expression System: E.coli
Tag: N-6His
Expression Range: 63-148aa
$429.99 $549.99
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SDS-PAGE analysis of Human HBEGF (Proheparin-Binding Egf-Like Growth Factor) - Recombinant Protein, showing >90% purity under 15% SDS-PAGE (Reduced)
Astor Scientific

Human HBEGF (Proheparin-Binding Egf-Like Growth Factor) - Recombinant Protein

$429.99 $549.99

Product Overview

Product Name Recombinant Human HBEGF Protein
Product Overview This recombinant human HBEGF protein includes amino acids 63-148aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization.
Target Uniprot Id Q99075
Recommended Name Proheparin-binding EGF-like growth factor
Gene Name HBEGF
Synonyms Heparin-binding EGF-like growth factor, DTR, DTS, DTSF, HEGFL
Species Human
Predicted Molecular Mass 12.1 kDa
Expression System E.coli
Expression Range 63-148aa
Tag N-6His
Purity >90%
Formulation Lyophilized
Buffer Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose
Storage Condition 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C.
Reconstitution Instruction Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%.
Applications Positive Control; Immunogen; SDS-PAGE; WB
Research Area Cancer
Target Function Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Subcellular Location [Heparin-binding EGF-like growth factor]: Secreted, extracellular space. Note=Mature HB-EGF is released into the extracellular space and probably binds to a receptor.; [Proheparin-binding EGF-like growth factor]: Cell membrane; Single-pass type I membrane protein.

Size

  • 100ug
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