Welcome to Astor Scientific

New collections added! Learn more

Astor Scientific  |  SKU: ASTP7637

Human GUK1 (Guanylate Kinase) - Recombinant Protein

Molecule: GUK1
Species: Human
Expression System: E.coli
Tag: N-6His
Expression Range: 1-197aa
$429.99 $549.99
Shipping calculated at checkout.

Payment & Security

Payment methods

  • American Express
  • Apple Pay
  • Diners Club
  • Discover
  • Google Pay
  • Mastercard
  • PayPal
  • Shop Pay
  • Venmo
  • Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.


Product Description


Product Reviews

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)
SDS-PAGE analysis of Human GUK1 (Guanylate Kinase) - Recombinant Protein, showing >90% purity under 15% SDS-PAGE (Reduced)
Astor Scientific

Human GUK1 (Guanylate Kinase) - Recombinant Protein

$429.99 $549.99

Product Overview

Product Name Recombinant Human GUK1 Protein
Product Overview This recombinant human GUK1 protein includes amino acids 1-197aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization.
Target Uniprot Id Q16774
Recommended Name Guanylate kinase
Gene Name GUK1
Synonyms Guanylate kinase, GMK, GMP kinase
Species Human
Predicted Molecular Mass 23.9 kDa
Expression System E.coli
Expression Range 1-197aa
Tag N-6His
Purity >90%
Formulation Lyophilized
Buffer Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose
Storage Condition 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C.
Reconstitution Instruction Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%.
Applications Positive Control; Immunogen; SDS-PAGE; WB
Research Area Cancer
Target Function Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP). Involved in the cGMP metabolism in photoreceptors. It may also have a role in the survival and growth progression of some tumors. In addition to its physiological role, GUK1 is essential for convert prodrugs used for the treatment of cancers and viral infections into their pharmacologically active metabolites, most notably acyclovir, ganciclovir, and 6-thioguanine and its closely related analog 6-mercaptopurine.
Subcellular Location Photoreceptor inner segment. Cytoplasm, cytosol.
Protein Family Guanylate kinase family
Tissue Specificity Widely expressed.

Size

  • 100ug
View product
close
close
close
I have a question
sparkles
close
product
Hello! I am very interested in this product.
gift
Special Deal!
sparkles