| Product Name |
Recombinant Human CECR1 (ADA2) Protein |
| Product Overview |
This recombinant human CECR1 (ADA2) protein includes amino acids 30-511aa of the target gene is expressed in Baculovirus-Insect Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q9NZK5 |
| Recommended Name |
Adenosine deaminase 2 |
| Gene Name |
ADA2 |
| Synonyms |
Adenosine deaminase CECR1 isoform, CECR1, ADA2, ADGF, IDGFL, PAN, SNEDS |
| Species |
Human |
| Predicted Molecular Mass |
56.9 kDa |
| Expression System |
Insect Cell |
| Expression Range |
30-511aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Epigenetics And Nuclear Signaling |
| Target Function |
Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity. |
| Subcellular Location |
Secreted. |
| Protein Family |
Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family, ADGF subfamily |
| Associated Diseases |
Polyarteritis nodosa (PAN); Sneddon syndrome (SNDDS) |
| Tissue Specificity |
Detected in blood plasma (at protein level). Widely expressed, with most abundant expression in human adult heart, lung, lymphoblasts, and placenta as well as fetal lung, liver, and kidney. In embryo, expressed in the outflow tract and atrium of the devel |
