| Product Name |
Recombinant Human Aminoacylase 2 (ACY2/ASPA) Protein |
| Product Overview |
This recombinant human Aminoacylase 2 (ACY2/ASPA) protein includes amino acids 1-313aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P45381 |
| Recommended Name |
Aspartoacylase |
| Gene Name |
ASPA |
| Synonyms |
Aspartoacylase, ACY2, ASP. |
| Species |
Human |
| Predicted Molecular Mass |
38.1 kDa |
| Expression System |
E.coli |
| Expression Range |
1-313aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids. |
| Subcellular Location |
Cytoplasm. Nucleus. |
| Protein Family |
AspA/AstE family, Aspartoacylase subfamily |
| Associated Diseases |
Canavan disease (CAND) |
| Tissue Specificity |
Brain white matter, skeletal muscle, kidney, adrenal glands, lung and liver. |
