| Product Name |
Recombinant Human Asialoglycoprotein Receptor 1 (ASGR1) Protein |
| Product Overview |
This recombinant human Asialoglycoprotein Receptor 1 (ASGR1) protein includes amino acids 62-291aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P07306 |
| Recommended Name |
Asialoglycoprotein receptor 1 |
| Gene Name |
ASGR1 |
| Synonyms |
Asialoglycoprotein Receptor 1; ASGP-R 1; ASGPR 1; C-Type Lectin Domain Family 4 Member H1; Hepatic L |
| Species |
Human |
| Predicted Molecular Mass |
27.4 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
62-291aa |
| Tag |
C-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
| Subcellular Location |
[Isoform H1a]: Membrane; Single-pass type II membrane protein.; [Isoform H1b]: Secreted. |
| Tissue Specificity |
Expressed exclusively in hepatic parenchymal cells. |
